The enteroviruses, of which there are over 70 serotypes, are RNA viruses of the Picornaviridae family and consist of the polioviruses and the non-polioviruses. The latter group includes coxsackie A and B, echoviruses and other enteroviruses. Widespread use of vaccination has resulted in elimination of the polioviruses from the Western Pacific, Americas and European Regions. On the other hand, non-polio enteroviruses are among the most common viral infections in humans. This group of viruses has a worldwide distribution but is more active in the late summer or early autumn in temperate climates.